Annual Class: required consecutive enrollment in fall (CTIV 5017 01) and in spring (CTIV 5017 03). Students must successfully complete both semesters of the course in order to receive credit.
This is a two‐part series that will provide a fundamental understanding of immunology. Immunology I will give a comprehensive overview of basic immunology beginning with innate immune responses followed by a study of the main aspects of acquired immunity. Important topics include the following: organization of lymphoid tissues and immune cell migration, cellular and molecular aspects of innate immunity, specific interactions of target cells and T cells that are regulated by the MHC molecule and peptide antigens on the target cell and the antigen specific T cell receptor; generation and molecular structure of B and T cell antigen receptors; signaling through immune receptors; the development of antigen specific T and B cells; and specific roles of some cytokines/lymphokines. The second part of the series is Immunology II, held in the Spring semester, which focuses on aspects of T and B effector cell generation, immune response generation and regulation in the context of infection, autoimmunity, tumor immunity, and transplant.